Terpinen-4-ol
Terpinen-4-ol is an isomer of terpineol, widely found in various natural plants, especially as the main active component of turpentine oil and tea tree oil, and also found in lavender oil and nutmeg oil. It typically appears as a pale yellow viscous liquid, emitting a mild earthy and woody odour, with fresh herbaceous, camphoraceous, and medicinal nuances.
In addition to its natural occurrence, Terpinen-4-ol can also be prepared by the hydration reaction of sabinene, or produced by the oxidation, hydrogenation reduction, and selective hydrogenation of terpinolene.
Substance Identification
Synonyms | 4-Terpinenol | Terpinenol-4 | ρ-1-Menthen-4-ol | Terpinenol-4 |
CAS | 562-74-3 |
EINECS | 209-235-5 |
FEMA | 2248 |
HS.CODE | 330129 |
Molecular Formula | C10H18O |
Moleclar Weight | 154.25 |
Toxicological Information
LD50 oral, rat | >1.3g/kg |
LD50 dermal, rabbit | >2.5g/kg |
Application & Uses
- Potent Natural Antimicrobial, Disinfectant & Preservative: Renowned for its significant disinfecting, sterilising, and antiseptic effects, it is the primary medicinal active component of Tea Tree Oil, and used as an intermediate to antibacterial agents and a natural preservative.
- Personal Care and Daily Chemical Products: Widely applied in body lotions, cleaners, shampoos, soaps, and various other personal hygiene products.
- Flavours, Fragrances & Essential Oil Blending: Utilised in flavour formulations such as mints, spices, and fruity citrus notes, and for the reconstitution of essential oils like lavender and geranium.
- Dermatological and Topical Treatments: As an effective topical ingredient, it is used in the treatment of skin infections, minor cuts, abrasions, acne, fungal infections (such as athlete's foot and ringworm), and for alleviating inflammation.
- Solvent Applications: Can be used as a bio-based solvent.
Features & Benefits
- Excellent Antimicrobial Properties: Exhibits significant disinfecting, sterilising, and antiseptic effects, making it ideal for various applications.
- Unique Solubility Profile: It is slightly soluble in water but readily soluble in alcohols and oils, offering flexibility in diverse formulations.
Sales Specification
ITEM | VALUE | TEST METHOD & UNIT |
---|---|---|
Apearance | Slightly yellow viscous liquid | |
Odor | Mild earthy, woody, musty, peppery | |
Refractive Index | 1.475 to 1.485 | @N20/d |
Density | 0.928 to 0.941 | @D20/4, g/ml |
Optical Rotation | -15 to -30 | ° |
Content | 98 min | @GC, % |
ITEM | VALUE | TEST METHOD & UNIT |
---|---|---|
Apearance | Slightly yellow viscous liquid | |
Odor | Mild earthy, woody, musty, peppery | |
Refractive Index | 1.475 to 1.485 | @N20/d |
Density | 0.928 to 0.941 | @D20/4, g/ml |
Optical Rotation | -0.5 to +0.5 | ° |
Content | 95 min | @GC, % |
Similar Specs
GHS Hazard Statements
H-Code | H227/302/315/319/335 |
P-Code | P210/261/264/270/271/280 |
Response | P301+P312+P330 P302+P352 P304+P340+P312 P305+P351+P338 P332+P313 P337+P313 P370+P378 |
Storage | P403+P233 P403+P235 P405 |
Disposal | P501 |
Storage
- Environmental Control: Store in a cool, dry, and well-ventilated place, and protect from light.
- Container Management: Keep containers tightly closed and clearly labelled. Opened containers must be carefully resealed and kept upright to prevent leakage.
- Inert Gas Protection: This product is air sensitive and must be stored under inert gas.
- Isolate from Hazards: Keep storage areas away from heat, sparks, open flames, and all incompatible materials.
- Safe Handling & Inspection: Handle carefully, and stack stably. After prolonged storage, always check quality before use.
- Compliance & Emergency: Strictly comply with all safety regulations, and ensure emergency plans are in place.
Relation Products
Relation Articles
- Terpinen-4-ol and alpha-terpineol (tea tree oil components) inhibit the production of IL-1beta, IL-6 and IL-10 on human macrophages
- R&D on Terpinen-4-ol
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