Cooling Agents WS-12
WS-12 ((1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide) is a synthetic compound designed to deliver a cooling sensation across various products. It offers the strong cooling effect, rated at strength 3.5. This effect lasts up to 36 minutes, providing ample time for a refreshing cooling experience.
WS-12 has Kosher ready.
Substance Identification
| Synonyms | (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide |
| CAS | 68489-09-8 |
| EINECS | 700-232-9 |
| FEMA | 4681 |
| HS.CODE | 292429 |
| Molecular Formula | C18H27NO2 |
| Moleclar Weight | 289.4 |
Application & Uses
-
Commonly used in mint-flavoured oral care fragrances, confectionery, and chewing gum. At low usage levels, imparts freshness to berry, citrus, and other fruit flavours.
- Oral care (toothpaste, mouthwash), cosmetics (creams, lotions), pharmaceuticals, personal care (shampoos, conditioners); enhances refreshing quality in food and drinks due to powerful cooling effect.
Features & Benefits
- Non-volatile, odourless, and tasteless; no cooling when tasted directly but activates when crushed into fine powder.
- Delivers impactful, fresh, long-lasting cooling (longest duration among WS series) without menthol's burning or pungent aftertaste; strongest initial effect with extended longevity compared to other WS agents.
- Enhances sustained cooling when combined with other WS agents; alone, exhibits poor solubility and heavy bitterness; more stable than menthol for consistent long-term cooling. Heat-resistant up to 200°C.
- Acts on front of tongue, entire oral mucosa, and throat.
| Recommended usage level | WS-12 | |
| min | max | |
| Fog-fluid | 1500 ppm | 30000 ppm |
| Beverage | 10 ppm | 100 ppm |
| Toothpaste | 5000 ppm | 40000 ppm |
| Mouthwash | 500 ppm | 10000 ppm |
| Hard candy | 100 ppm | 2000 ppm |
| Chewing gum | 1500 ppm | 30000 ppm |
| Creams & Lotions | 50000 ppm | 500000 ppm |
Sales Specification
| ITEM | VALUE | TEST METHOD & UNIT |
|---|---|---|
| Cooling Strength | 3.5 | @Menthol was set as 1 as a reference |
| Cooling Longevity | 36 | minutes |
| ITEM | VALUE | TEST METHOD & UNIT |
|---|---|---|
| Cooling Strength | 1.5 | @Menthol was set as 1 as a reference |
| Cooling Longevity | 6 | minutes |
| ITEM | VALUE | TEST METHOD & UNIT |
|---|---|---|
| Cooling Strength | 4 | @Menthol was set as 1 as a reference |
| Cooling Longevity | 10 | minutes |
| ITEM | VALUE | TEST METHOD & UNIT |
|---|---|---|
| Cooling Strength | 4.5 | @Menthol was set as 1 as a reference |
| Cooling Longevity | 12 | minutes |
| ITEM | VALUE | TEST METHOD & UNIT |
|---|---|---|
| Cooling Strength | 0.75 | @Menthol was set as 1 as a reference |
| Cooling Longevity | 8 | minutes |
GHS Hazard Statements
Storage
- Flammable materials should be stored in a separate safety storage cabinet or room
- Ground all equipment containing material
- Keep away from heat
- Keep away from sources of ignition
- Keep container tightly closed
- Keep in a cool, well-ventilated place
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