Cooling Agents WS-12

WS-12 ((1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide) is a synthetic compound designed to deliver a cooling sensation across various products. It offers the strong cooling effect, rated at strength 3.5. This effect lasts up to 36 minutes, providing ample time for a refreshing cooling experience.

WS-12 has Kosher ready.

Substance Identification

Synonyms (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide
CAS 68489-09-8
EINECS 700-232-9
FEMA 4681
HS.CODE 292429
Molecular Formula C18H27NO2
Moleclar Weight 289.4

Application & Uses

  • Commonly used in mint-flavoured oral care fragrances, confectionery, and chewing gum.​ At low usage levels, imparts freshness to berry, citrus, and other fruit flavours.

  • Oral care (toothpaste, mouthwash), cosmetics (creams, lotions), pharmaceuticals, personal care (shampoos, conditioners); enhances refreshing quality in food and drinks due to powerful cooling effect.

Features & Benefits

  • Non-volatile, odourless, and tasteless; no cooling when tasted directly but activates when crushed into fine powder.
  • Delivers impactful, fresh, long-lasting cooling (longest duration among WS series) without menthol's burning or pungent aftertaste; strongest initial effect with extended longevity compared to other WS agents.​
  • Enhances sustained cooling when combined with other WS agents; alone, exhibits poor solubility and heavy bitterness; more stable than menthol for consistent long-term cooling. Heat-resistant up to 200°C.
  • Acts on front of tongue, entire oral mucosa, and throat.
 
Recommended usage level WS-12
min max
Fog-fluid 1500 ppm 30000 ppm
Beverage 10 ppm 100 ppm
Toothpaste 5000 ppm 40000 ppm
Mouthwash 500 ppm 10000 ppm
Hard candy 100 ppm 2000 ppm
Chewing gum 1500 ppm 30000 ppm
Creams & Lotions 50000 ppm 500000 ppm

Sales Specification

ITEM VALUE TEST METHOD & UNIT
Cooling Strength 3.5 @Menthol was set as 1 as a reference
Cooling Longevity 36 minutes
ITEM VALUE TEST METHOD & UNIT
Cooling Strength 1.5 @Menthol was set as 1 as a reference
Cooling Longevity 6 minutes
ITEM VALUE TEST METHOD & UNIT
Cooling Strength 4 @Menthol was set as 1 as a reference
Cooling Longevity 10 minutes
ITEM VALUE TEST METHOD & UNIT
Cooling Strength 4.5 @Menthol was set as 1 as a reference
Cooling Longevity 12 minutes
ITEM VALUE TEST METHOD & UNIT
Cooling Strength 0.75 @Menthol was set as 1 as a reference
Cooling Longevity 8 minutes

Package

  • Customizable packaging details.

Preview all the spec of packaging

GHS Hazard Statements

Storage

  • Flammable materials should be stored in a separate safety storage cabinet or room
  • Ground all equipment containing material
  • Keep away from heat
  • Keep away from sources of ignition
  • Keep container tightly closed
  • Keep in a cool, well-ventilated place

Relation Articles


Remark

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The above information is believed to be accurate and represents the best explanation currently available to us. However, no liability is assumed for any consequences arising from the use of this content. The technical standards for our products are developed and updated jointly by our customers and ourselves; where any changes occur, the latest specification shall prevail and will be confirmed in the relevant contract.All suggestions and data provided are based on information we consider to be reliable and are offered in good faith, but without any guarantee, as the conditions and methods of use of our products are beyond our control. Foreverest® makes no warranties, whether express or implied, regarding the accuracy, completeness or suitability of this information, and expressly disclaims any implied warranty of fitness for a particular purpose. Prospective users should conduct their own tests and evaluations to determine the suitability of Foreverest® materials and any recommendations for their intended applications before adoption, and, where appropriate, should obtain confirmation or approval from the relevant regulatory authorities.Any references in this page to patents or patented technologies, including descriptive material derived from patents or citations of specific patent numbers, are provided for information only. They must not be interpreted as a recommendation to use our products in a manner that could infringe any third‑party patent, nor as a grant of any licence or permission to use patents owned by Foreverest®.

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